Polymorph Applications: The Mexican Approach.

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Polymorph Applications: The Mexican Approach.

In the summer of 1998, Abbot Laboratories was forced to remove from the market a first crystalline form of its medicament ritonavir, a peptidomimetic drug used to treat HIV-1 infection, in favor of a second molecular form, or polymorph, which had different dissolution properties. The fir...

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